• About Natto MK-7
  • Health Benefits
    • Cardiovascular Health
    • Bone Health
    • Kidney Health
    • Cutting-edge Research
  • About Vitamin K
    • Vitamin K
    • Vitamin K2
    • History of Vitamin K
    • Vitamin K2 vs K1
    • MK-7 vs MK-4
    • Vitamin K2 and Calcium
    • Vitamin K2 Deficiency
    • Real Source of MK-7
  • News & Library
    • Event
    • News & Download Center
    • References
  • Contact Us
Menu
  • About Natto MK-7
  • Health Benefits
    • Cardiovascular Health
    • Bone Health
    • Kidney Health
    • Cutting-edge Research
  • About Vitamin K
    • Vitamin K
    • Vitamin K2
    • History of Vitamin K
    • Vitamin K2 vs K1
    • MK-7 vs MK-4
    • Vitamin K2 and Calcium
    • Vitamin K2 Deficiency
    • Real Source of MK-7
  • News & Library
    • Event
    • News & Download Center
    • References
  • Contact Us

News & Library

You can find out everything here!

Table of Contents

News

Vitamin K and the Management of Patients with Cystic Fibrosis
August 26, 2023 7:05 pm

VITAMIN K AND THE MANAGEMENT OF PATIENTS WITH CYSTIC FIBROSIS Objective:To assess the advisability of routine vitamin K supplementation in patients with cystic fibrosis (CF). Data Sources: Studies identified through a MEDLINE search with the use of MeSH terms vitamin K, cystic fibrosis, PIVKA-II (protein induced by vitamin k absence-II),

Read More »
Vitamin K2 (menaquinone, MK) Intake Could Reduce Coronary Calcification
August 22, 2023 5:38 pm

Journal Article: High dietary menaquinone intake is associated with reduced coronary calcification. Background: Dietary vitamin K is thought to decrease risk of cardiovascular disease by reducing coronary calcification, but inconsistent results are reported. This may be due to different effects of vitamin K1 (phylloquinone) and vitamin K2 (menaquinone, MK), but

Read More »
Vitamin K in Breast Milk
August 15, 2023 5:27 pm

VITAMIN K2 (MENAQUINONE, MK) INTAKE COULD REDUCE CORONARY CALCIFICATION For many children, breast-feeding is their sole source of vitamin K. Breast-fed infants are at risk for vitamin K-responsive Hemorrhagic Disease of the Newborn (HDNB). Recent advances in technology have made it possible for the first quantitative studies to be done

Read More »
Vitamin K Intake Related to Bone Mass in Girls
August 12, 2023 8:17 pm

VITAMIN K INTAKE RELATED TO BONE MASS IN GIRLS Vitamin K has long been associated with its role in bone metabolism. Lack of vitamin K intake has also been related to low bone density and osteoporotic fracture risk.  A study from The American Journal of Clinical Nutrition postulates that vitamin

Read More »
First non-GMO Project Verified Vitamin K2 (MK-7) & Nattokinase
March 11, 2023 6:12 pm

The First Vitamin K2 (MK-7) and Nattokinase to be non-GMO Project Verified PRESS RELEASE        Indianapolis IN, February 25, 2014:  Nongmoproject.org has certified Vesta Ingredients’ MK-7 and Nattokinase as GMO free, continuing to separate these high quality products from competitors.  The MK-7 reputation is growing, but there is more

Read More »
Short Vitamin K2 (MK-7) Presentation
March 8, 2023 4:48 pm

Download Center Short Vitamin K2 (MK-7) Presentation This video was debuted at Engredea 2013. DOWNLOAD contact us anytime If you have any questions, please feel free to contact us. We would be happy to answer any of your questions and discuss how we can help you meet your dietary supplement

Read More »

Download Center

Short Vitamin K2 (MK-7) Presentation
March 8, 2023 No Comments

Download Center Short Vitamin K2 (MK-7) Presentation This video was debuted at Engredea 2013. DOWNLOAD contact us anytime If you have any questions, please feel free to contact us. We

Read More »
Vitamin K2 Video Presentation
March 4, 2023 No Comments

Download Center the mechanisms by which Vitamin K2 regulates calcium in our bodies Originally presented by Dr. Ralph Holsworth, scientific adviser for Vesta Ingredients, this video delves deep into the

Read More »
nattoMK-7 Product Brochure
March 4, 2023 No Comments

Download Center Natto mk-7 product brochure Learn all about the benefits of Vitamin K2 (MK-7) as well as Vesta’s nattoMK-7 We will not bother you with introductory emails. Unless you

Read More »
nattoMK-7 Flyer
March 1, 2023 No Comments

Download Center An one-page flyer describing Vesta’s nattoMK-7. All-in-one to understand Vesta’s Natto MK-7 instead of waiting for lengthy emails. We are proud to introduce to you The Natto MK-7

Read More »
Join our newsletter to stay updated

References

  1. Misra D, et al. Vitamin k deficiency is associated with incident knee osteoarthritis. American Journal of Medicine, 2013 Mar;126(3):243-8 doi:10.1016/j.amjmed.2012.10.011
  2. Fusaro M, et al. Vitamin K, vertebral fractures, vascular calcifications, and mortality: Vitamin K Italian (VIKI) dialysis study. Journal of Bone Miner Res. 2012 Nov; 27(11):2271-8. doi: 10.1002/jbmr.1677
  3. Steven M. Plaza, ND, LAc, and Davis W. Lamson, MS, ND. Vitamin K2 in Bone Metabolism and Osteoporosis. Altern Med Rev 2005;10(1):24-35
  4. Iwamoto,, Ichiro, and Et. Al. “A Longitudinal Study of the Effect of Vitamin K2 on Bone Mineral Density in Postmenopausal Women a Comparative Study with Vitamin D3 and Estrogen–progestin Therapy.” The Official Journal of the European Menopause and Andropause Society, 30 Jan. 2009.
  5. Schurgers LJ, Teunissen KJ, Hamulyak K, Knapen MH, Vik H, Vermeer C., Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7., Blood. 2007 Apr 15;109(8):3279-83.
  6. Mann KG (1999). “Biochemistry and physiology of blood coagulation”. Thromb. Haemost. 82 (2): 165–74.
  7. Price PA (1988). “Role of vitamin-K-dependent proteins in bone metabolism”. Annu. Rev. Nutr. 8: 565–83. doi:10.1146/annurev.nu.08.070188.003025.
  8. Hafizi S, Dahlbäck B (2006). “Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily”. FEBS J. 273 (23): 5231–44.doi:10.1111/j.1742-4658.2006.05529.x.
  9. Gast, G., N. Roos, I. Sluijs, M. Bots, J. Beulens, J. Geleijnse, J. Witteman, D. Grobbee, P. Peeters, and Y. Van Der Schouw. “A High Menaquinone Intake Reduces the Incidence of Coronary Heart Disease.” A High Menaquinone Intake Reduces the Incidence of Coronary Heart Disease. Nutrition, Metabolism, and Cardiovascular Diseases, 30 Jan. 2009.
  10. Xing G, Gutala R, Jaiswal A. Quinone Oxidoreductases and Vitamin K Metabolism. Vitamins & Hromones Vol 78, 2008, Pages 85-101.
  11. University of Maryland Medical Center . Vitamin K Overview 2005 http://www.umm.edu/altmed/articles/vitamin-k-000343.htm
  12. Dam, H. (1935). “The Antihæmorrhagic Vitamin of the Chick.: Occurrence And Chemical Nature”. Nature 135(3417): 652–653. doi:10.1038/135652b0.
  13. Ichikawa T, Horie-Inoue K, Ikeda K,, Blumberg B, and Inoue S. “Steroid and Xenobiotic Receptor SXR Mediates Vitamin K2-activated Transcription of Extracellular Matrix-related Genes and Collagen Accumulation in Osteoblastic Cells.”Steroid and Xenobiotic Receptor SXR Mediates Vitamin K2-activated Transcription of Extracellular Matrix-related Genes and Collagen Accumulation in Osteoblastic Cells. J Biol Chem, 2006 Jun 23;281(25):16927-34. Epub 2006 Apr 10.
  14. Vitamin K2. 2/18/2013 http://www.vitamink2.org/?znfAction=references
  15. Booth SL, Suttie JW. Dietary Intake and Adequacy of K vitamins. Journal of Nutrition. 1998;128(5):785-8.
  16. Kaneki M, Hodges SJ, Hosoi T, Fujiwara S, Lyons A, Crean SJ, Ishida N, Nakagawa M, Takechi M, Sano Y, Mizuno Y, Hoshino S, Miyao M, Inoue S, Horiki K, Shiraki M, Ouchi Y, Orimo H. Japanese fermented soybean food as the major determinant of the large geographic difference in circulating levels of K vitamins2: possible implications for hip-fracture risk. Nutrition. 2001;17(4):315-21.
  17. Olson RE. Vitamin K. In: Shils M, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. 9th ed. Baltimore: Lippincott Williams & Wilkins; 1999:363-380.
  18. Furie B, Bouchard BA, Furie BC. Vitamin K-dependent biosynthesis of gamma-carboxyglutamic acid. Blood. 1999;93(6):1798-1808.
  19. Shearer MJ. The roles of vitamins D and K in bone health and osteoporosis prevention. Proc Nutr Soc. 1997;56(3):915-937.
  20. Schurgers LJ, Spronk HM, Soute BA, et al. Regression of warfarin-induced medial elastocalcinosis by high intake of K vitamins in rats. Blood. Nov 30 2006.
  21. Westenfeld, R., L. Schurgers, and Et Al. “Effect of Vitamin K2 Supplementation on Functional Vitamin K Deficiency in Hemodialysis Patients: A Randomized Trial.” American Journal of Kidney Disease, 12 Dec. 2011.
  22. Beulens, Joline W.J., Michiel L. Bots, Femke Atsma, Marie-Louise E.L. Bartelink, Matthias Prokop, Johanna M. Geleijnse, Jacqueline C.M. Witteman, Diederick E. Grobbee, and Yvonne T. Van Der Schouw. “High Dietary Menaquinone Intake Is Associated with Reduced Coronary Calcification.” Atherosclerosis 203.2 (2009): 489-93.
  23. Geleijnse JM, Witteman JC, and Et Al. “Dietary Intake of Menaquinone Is Associated with a Reduced Risk of Coronary Heart Disease: The Rotterdam Study.” The Journal of Nutrition (n.d.): n. pag.
  24. Vermeer C, Theuwissen E. “Vitamin K, Osteoporosis and Degenerative Diseases of Ageing.” Menopause Int. 2011 Mar;17(1):19-23. (n.d.)
  25. Center for Disease Control. Osteoporosis. http://www.cdc.gov/nchs/fastats/osteoporosis.htm
  26. Knapen MHJ, Schurgers LJ, and Vermeer C, Vitamin K2 supplementation improves hip bone geometry and bone strength indices in postmenopausal women. Osteoporos Int, 2007, 18:953-972
  27. Fusaro, M., G. Crepaldi, S. Maggi, F. Galli, A. D’Angelo, L. Calò, S. Giannini, D. Miozzo, and M. Gallieni. “Journal of Endocrinological Investigation.” Journal of Endocrinological Investigation. N.p., 2011. Web. 30 July 2012.
  28. Ketteler, Markus, Hansjörg Rothe, Thilo Krüger, Patrick Biggar, and Georg Schlieper. “Mechanisms and Treatment of Extraosseous Calcification in Chronic Kidney Disease.” Nature, Sept. 2011.
  29. Sato, Jun Iwamoto, Azusa Seki, Yoshihiro, and Hideo Matsumoto. “Vitamin K2 Improves Renal Function and Increases Femoral Bone Strength in Rats with Renal Insufficiency.” SpringerLink. Springer Science+Business Media, n.d. Web. 30 July 2012.
  30. Yoshiji, Hitoshi, Ryuichi Noguchi, Masahito Uemura, and Hiroshi Fukui. “Combination of Vitamin K2 and Angiotensin-converting Enzyme Inhibitor Ameliorates Cumulative Recurrence of Hepatocellular Carcinoma.” Journal of Hepatology, 15 May 2009.
  31. Yoshiji, Hitoshi, Ryuichi Noguchi, Masaharu Yamazaki, Yasuhide Ikenaka, Akira Mitoro, Masahisa Toyohara, Motoyuki Yoshida, and Hiroshi Fukui. “Combined Treatment of Vitamin K2 and Angiotensin-converting Enzyme Inhibitor Ameliorates Hepatic Dysplastic Nodule in a Patient with Liver Cirrhosis.” World J Gastroenterol, 21 June 2007. Web. 30 July 2012.
  32. Nimptsch, K., and Et Al. “The American Journal of Clinical Nutrition.” Dietary Vitamin K Intake in Relation to Cancer Incidence and Mortality: Results from the Heidelberg Cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Heidelberg). The American Journal of Clinical Nutrition, n.d. Web.
  33. Vos, Melissa, and Patrik Verstreken. “Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency.” Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency. N.p., 10 May 2012. Web. 30 July 2012. http://www.sciencemag.org/content/336/6086/1306.figures-only.
  34. Hosking, Richard. A Dictionary of Japanese Food – Ingredients and Culture. 1995. Tuttle. p 106. ISBN 0-8048-2042-2
  35. Elder SJ, Haytowitz DB, Howe J, Peterson JW, Booth SL. Vitamin K contents of meat, dairy, and fast food in the U.S. Diet. Journal of Agricultural Food Chem. 54 (2): 463-7 doi:10.1021/jf052400h
  36. Ikeda Y, Iki M, Morita A, Kajita E, Kagamimori S, Kagawa Y, Yoneshima H. Intake of fermented soybeans, natto is associated with reduced bone loss in postmenopausal women: Japanese Population-Based Osteoporosis (JPOS) Study. Journal of Nutrition. 2006 May;136(5): 1323-8
  37. Tsukamoto Y, et al. Intake of fermented soybean (natto) increases circulating vitamin K2 (menaquinone-7) and gamma-carboxylated osteocalcin cocentration in normal individuals. Journal Bone Mineral Metabolism. 2000;18(4):216-22.
  38. “Rhéaume-Bleue, Kate. “Vitamin K2 and the Calcium Paradox” John Wiley & Sons Canada, Ltd., 2012, p. 66-67
  39. Buerk, Roland (11 March 2010). “Japan opens 98th national airport in Ibaraki”. BBC News. Retrieved 25 December 2012. “… natto, a fermented soy bean dish that many consider an acquired taste.”
  40. Katz, Sandor Ellix (2012). The Art of Fermentation: An In-Depth Exploration of Essential Concepts and Processes from Around the World. Chelsea Green Publishing. pp. 328–329. ISBN 978-1603582865. “Natto is a Japanese soy ferment that produces a slimy, mucilagenous coating on the beans, something like okra. […] The flavor of natto carries notes of ammonia (like some cheeses or overripe tempeh), which gets stronger as it ferments longer.”
contact us anytime

If you have any questions, please feel free to contact us. We would be happy to answer any of your questions and discuss how we can help you meet your dietary supplement and nutraceutical manufacturing needs. We are confident that Vesta can be your trusted partner in the dietary supplement and nutraceutical industry. Please fill out this quick form today to learn more about our services.

 
Facebook-f Instagram Linkedin Youtube
back to top
© 2024 Vesta Natto MK-7™ | All Right Reserved